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Research ArticlePriority Updates from the Research Literature (PURLS)

Are Single-Pill Antihypertensive Combinations Superior to Multi-Pill Regimens at Reducing All-Cause Mortality and Cardiovascular Events?

Alejandra Espinoza, Cate Lynn and Sara Neal
The Journal of the American Board of Family Medicine November 2025, 38 (6) 1117-1119; DOI: https://doi.org/10.3122/jabfm.2025.250332R0
Alejandra Espinoza
From the Cone Health Program, Greensboro, NC (AE, CL, SN).
DO
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Cate Lynn
From the Cone Health Program, Greensboro, NC (AE, CL, SN).
MD, MPH, MA
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Sara Neal
From the Cone Health Program, Greensboro, NC (AE, CL, SN).
MD, MA, CAQSM
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References

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    , ESC Scientific Document Groupet al. ESC/ESH guidelines for the management of arterial hypertension. Eur Heart J 2018;39:3021–104.
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    1. Baker-Goering MM,
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    . Relationship between adherence to antihypertensive medication regimen and out-of-pocket costs among people aged 35 to 64 with employer-sponsored health insurance. Prev Chronic Dis 2019;16:E32. Available at: http://dx.doi.org/10.5888/pcd16.180381.
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    1. Schroeder K,
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    , Cochrane Hypertension Group. Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings. Cochrane Database Syst Rev 2004;2010. Available from EBM Reviews - Cochrane Database of Systematic Reviews. Accessed February 13.
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    OpenUrlFREE Full Text
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The Journal of the American Board of Family   Medicine: 38 (6)
The Journal of the American Board of Family Medicine
Vol. 38, Issue 6
November-December 2025
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Are Single-Pill Antihypertensive Combinations Superior to Multi-Pill Regimens at Reducing All-Cause Mortality and Cardiovascular Events?
Alejandra Espinoza, Cate Lynn, Sara Neal
The Journal of the American Board of Family Medicine Nov 2025, 38 (6) 1117-1119; DOI: 10.3122/jabfm.2025.250332R0

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Are Single-Pill Antihypertensive Combinations Superior to Multi-Pill Regimens at Reducing All-Cause Mortality and Cardiovascular Events?
Alejandra Espinoza, Cate Lynn, Sara Neal
The Journal of the American Board of Family Medicine Nov 2025, 38 (6) 1117-1119; DOI: 10.3122/jabfm.2025.250332R0
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