Research ArticleOriginal Research

Is Cognitive Impairment Associated with Inadequate Bowel Preparation for Colonoscopy?

Jeanette M. Daly, Yinghui Xu, Seth D. Crockett, Richard M. Hoffman and Barcey T. Levy
The Journal of the American Board of Family Medicine May 2025, 38 (3) 423-430; DOI: https://doi.org/10.3122/jabfm.2024.240338R1

References

  1. 1.↵
    1. Qaseem A,
    2. Crandall CJ,
    3. Mustafa RA
    , Clinical Guidelines Committee of the American College of Physicianset al. Screening for colorectal cancer in asymptomatic average-risk adults: a guidance statement from the American College of Physicians. Ann Intern Med 2019;171:643–54.
    OpenUrlCrossRefPubMed
  2. 2.↵
    1. Clark BT,
    2. Rustagi T,
    3. Laine L
    . What level of bowel prep quality requires early repeat colonoscopy: systematic review and meta-analysis of the impact of preparation quality on adenoma detection rate. Am J Gastroenterol 2014;109:1714–23; quiz 1724.
    OpenUrlCrossRefPubMed
  3. 3.↵
    1. Harewood GC,
    2. Sharma VK,
    3. de Garmo P
    . Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia. Gastrointest Endosc 2003;58:76–9.
    OpenUrlCrossRefPubMedWeb of Science
  4. 4.↵
    1. Yee R,
    2. Manoharan S,
    3. Hall C,
    4. Hayashi A
    . Optimizing bowel preparation for colonoscopy: what are the predictors of an inadequate preparation? Am J Surg 2015;209:787–92; discussion 792.
    OpenUrlPubMed
  5. 5.↵
    1. Ness RM,
    2. Manam R,
    3. Hoen H,
    4. Chalasani N
    . Predictors of inadequate bowel preparation for colonoscopy. Am J Gastroenterol 2001;96:1797–802.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.
    1. Sherer EA,
    2. Imler TD,
    3. Imperiale TF
    . The effect of colonoscopy preparation quality on adenoma detection rates. Gastrointest Endosc 2012;75:545–53.
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Appannagari A,
    2. Mangla S,
    3. Liao C,
    4. Reddy KG,
    5. Kupfer SS
    . Risk factors for inadequate colonoscopy bowel preparations in African Americans and Whites at an urban medical center. South Med J 2014;107:220–4.
    OpenUrlPubMed
  8. 8.↵
    1. Fayad NF,
    2. Kahi CJ,
    3. Abd El-Jawad KH,
    4. et al
    . Association between body mass index and quality of split bowel preparation. Clin Gastroenterol Hepatol 2013;11:1478–85.
    OpenUrlPubMed
  9. 9.↵
    1. Lebwohl B,
    2. Kastrinos F,
    3. Glick M,
    4. Rosenbaum AJ,
    5. Wang T,
    6. Neugut AI
    . The impact of suboptimal bowel preparation on adenoma miss rates and the factors associated with early repeat colonoscopy. Gastrointest Endosc 2011;73:1207–14.
    OpenUrlCrossRefPubMed
  10. 10.↵
    1. Borg BB,
    2. Gupta NK,
    3. Zuckerman GR,
    4. Banerjee B,
    5. Gyawali CP
    . Impact of obesity on bowel preparation for colonoscopy. Clin Gastroenterol Hepatol 2009;7:670–5.
    OpenUrlCrossRefPubMed
  11. 11.↵
    1. Govani SM,
    2. Elliott EE,
    3. Menees SB,
    4. et al
    . Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy. World J Gastrointest Endosc 2016;8:616–22.
    OpenUrlPubMed
  12. 12.↵
    1. Kushnir VM,
    2. Bhat P,
    3. Chokshi RV,
    4. et al
    . The impact of opiate pain medications and psychoactive drugs on the quality of colon preparation in outpatient colonoscopy. Dig Liver Dis 2014;46:56–61.
    OpenUrlPubMed
  13. 13.↵
    1. Nguyen DL,
    2. Wieland M
    . Risk factors predictive of poor quality preparation during average risk colonoscopy screening: the importance of health literacy. J Gastrointestin Liver Dis 2010;19:369–72.
    OpenUrlPubMed
  14. 14.
    1. Siddiqui AA,
    2. Yang K,
    3. Spechler SJ,
    4. et al
    . Duration of the interval between the completion of bowel preparation and the start of colonoscopy predicts bowel-preparation quality. Gastrointest Endosc 2009;69:700–6.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.↵
    1. Yadlapati R,
    2. Johnston ER,
    3. Gregory DL,
    4. Ciolino JD,
    5. Cooper A,
    6. Keswani RN
    . Predictors of inadequate inpatient colonoscopy preparation and its association with hospital length of stay and costs. Dig Dis Sci 2015;60:3482–90.
    OpenUrlPubMed
  16. 16.↵
    1. Kazarian ES,
    2. Carreira FS,
    3. Toribara NW,
    4. Denberg TD
    . Colonoscopy completion in a large safety net health care system. Clin Gastroenterol Hepatol 2008;6:438–42.
    OpenUrlCrossRefPubMed
  17. 17.↵
    1. Baker FA,
    2. Mari A,
    3. Nafrin S,
    4. et al
    . Predictors and colonoscopy outcomes of inadequate bowel cleansing: a 10-year experience in 28,725 patients. Ann Gastroenterol 2019;32:457–62.
    OpenUrlPubMed
  18. 18.
    1. Sim JS,
    2. Koo JS
    . Predictors of inadequate bowel preparation and salvage options on colonoscopy. Clin Endosc 2016;49:346–9.
    OpenUrlPubMed
  19. 19.
    1. Martel M,
    2. Menard C,
    3. Restellini S,
    4. et al
    . Which patient-related factors determine optimal bowel preparation? Curr Treat Options Gastroenterol 2018;16:406–16.
    OpenUrlPubMed
  20. 20.↵
    1. Gandhi K,
    2. Tofani C,
    3. Sokach C,
    4. Patel D,
    5. Kastenberg D,
    6. Daskalakis C
    . Patient characteristics associated with quality of colonoscopy preparation: a systematic review and meta-analysis. Clin Gastroenterol Hepatol 2018;16:357–69.e10.
    OpenUrlPubMed
  21. 21.↵
    1. Zhang YY,
    2. Niu M,
    3. Wu ZY,
    4. Wang XY,
    5. Zhao YY,
    6. Gu J
    . The incidence of and risk factors for inadequate bowel preparation in elderly patients: a prospective observational study. Saudi J Gastroenterol 2018;24:87–92.
    OpenUrlPubMed
  22. 22.
    1. Arias F,
    2. Riverso M,
    3. Levy SA,
    4. et al
    . Pilot study: neurocognitive disorders and colonoscopy in older adults. Anesth Analg 2019;129:e89–e93.
    OpenUrlPubMed
  23. 23.↵
    1. Lai EJ,
    2. Calderwood AH,
    3. Doros G,
    4. Fix OK,
    5. Jacobson BC
    . The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research. Gastrointest Endosc 2009;69:620–5.
    OpenUrlCrossRefPubMed
  24. 24.↵
    1. van Rijn JC,
    2. Reitsma JB,
    3. Stoker J,
    4. Bossuyt PM,
    5. van Deventer SJ,
    6. Dekker E
    . Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol 2006;101:343–50.
    OpenUrlCrossRefPubMedWeb of Science
  25. 25.
    1. Froehlich F,
    2. Wietlisbach V,
    3. Gonvers JJ,
    4. Burnand B,
    5. Vader JP
    . Impact of colonic cleansing on quality and diagnostic yield of colonoscopy: the European Panel of Appropriateness of Gastrointestinal Endoscopy European multicenter study. Gastrointest Endosc 2005;61:378–84.
    OpenUrlCrossRefPubMedWeb of Science
  26. 26.↵
    1. Chokshi RV,
    2. Hovis CE,
    3. Hollander T,
    4. Early DS,
    5. Wang JS
    . Prevalence of missed adenomas in patients with inadequate bowel preparation on screening colonoscopy. Gastrointest Endosc 2012;75:1197–203.
    OpenUrlCrossRefPubMed
  27. 27.↵
    1. Sadeghi A,
    2. Rajabnia M,
    3. Bagheri M,
    4. et al
    . Predictive factors of inadequate bowel preparation for elective colonoscopy. Gastroenterol Hepatol Bed Bench. 2022;15:66–78.
    OpenUrlPubMed
  28. 28.↵
    1. Chan WK,
    2. Saravanan A,
    3. Manikam J,
    4. Goh KL,
    5. Mahadeva S
    . Appointment waiting times and education level influence the quality of bowel preparation in adult patients undergoing colonoscopy. BMC Gastroenterol 2011;11:86.
    OpenUrlCrossRefPubMed
  29. 29.↵
    1. Kumar A,
    2. Lin L,
    3. Bernheim O,
    4. et al
    . Effect of functional status on the quality of bowel preparation in elderly patients undergoing screening and surveillance colonoscopy. Gut Liver 2016;10:569–73.
    OpenUrlPubMed
  30. 30.↵
    1. Woo DH,
    2. Kim KO,
    3. Jeong DE,
    4. et al
    . Prospective analysis of factors associated with inadequate bowel preparation for colonoscopy in actual clinical practice. Intest Res 2018;16:293–8.
    OpenUrlPubMed
  31. 31.
    1. Chung YW,
    2. Han DS,
    3. Park KH,
    4. et al
    . Patient factors predictive of inadequate bowel preparation using polyethylene glycol: a prospective study in Korea. J Clin Gastroenterol 2009;43:448–52.
    OpenUrlCrossRefPubMed
  32. 32.↵
    1. Hassan C,
    2. Fuccio L,
    3. Bruno M,
    4. et al
    . A predictive model identifies patients most likely to have inadequate bowel preparation for colonoscopy. Clin Gastroenterol Hepatol 2012;10:501–6.
    OpenUrlCrossRefPubMed
  33. 33.↵
    1. Dik VK,
    2. Moons LM,
    3. Hüyük M
    , Colonoscopy Quality Initiativeet al. Predicting inadequate bowel preparation for colonoscopy in participants receiving split-dose bowel preparation: development and validation of a prediction score. Gastrointest Endosc. 2015;81:665–72.
    OpenUrlCrossRefPubMed
  34. 34.↵
    1. Hernández G,
    2. Gimeno-García AZ,
    3. Quintero E
    . Strategies to improve inadequate bowel preparation for colonoscopy. Front Med (Lausanne) 2019;6:245.
    OpenUrlPubMed
  35. 35.
    1. Guo X,
    2. Yang Z,
    3. Zhao L,
    4. et al
    . Enhanced instructions improve the quality of bowel preparation for colonoscopy: a meta-analysis of randomized controlled trials. Gastrointest Endosc 2017;85:90–7.e6.
    OpenUrlPubMed
  36. 36.↵
    1. Chang CW,
    2. Shih SC,
    3. Wang HY,
    4. et al
    . Meta-analysis: the effect of patient education on bowel preparation for colonoscopy. Endosc Int Open 2015;3:E646–52.
    OpenUrl
  37. 37.↵
    1. Daly JM,
    2. Xu X,
    3. Crockett SD,
    4. Schmidt ME,
    5. Kim P,
    6. Levy BT
    . Clock-drawing test as a screening tool for cognitive impairment associated with fecal immunochemical test collection errors. Ann Fam Med 2022;20:452–9.
    OpenUrlAbstract/FREE Full Text
  38. 38.↵
    1. Levy BT,
    2. Daly JM,
    3. Xu Y,
    4. et al
    . Comparative effectiveness of five fecal immunochemical tests using colonoscopy as the gold standard: study protocol. Contemp Clin Trials. 2021;106:106430.
    OpenUrlCrossRefPubMed
  39. 39.↵
    1. Daly JM,
    2. Parang K,
    3. Levy BT
    . Electronic health record algorithm development for research subject recruitment using colonoscopy appointment scheduling. J Am Board Fam Med 2021;34:49–60.
    OpenUrlAbstract/FREE Full Text
  40. 40.↵
    1. Levy BT,
    2. Xu Y,
    3. Daly JM,
    4. et al
    . Comparative performance of common fecal immunochecmical tests: a cross-sectional study. Ann Intern Med 2024;177:1350–60.
    OpenUrlPubMed
  41. 41.↵
    1. Levy BT,
    2. Xu Y,
    3. Daly JM,
    4. Ely JW
    . A randomized controlled trial to improve colon cancer screening in rural family medicine: an Iowa Research Network (IRENE) study. J Am Board Fam Med 2013;26:486–97.
    OpenUrlAbstract/FREE Full Text
  42. 42.↵
    1. Watson YI,
    2. Arfken CL,
    3. Birge SJ
    . Clock completion: an objective screening test for dementia. J Am Geriatr Soc 1993;41:1235–40.
    OpenUrlCrossRefPubMedWeb of Science
  43. 43.↵
    1. Mendes-Santos LC,
    2. Mograbi D,
    3. Spenciere B,
    4. Charchat-Fichman H
    . Specific algorithm method of scoring the Clock Drawing Test applied in cognitively normal elderly. Dement Neuropsychol 2015;9:128–35.
    OpenUrlPubMed
  44. 44.↵
    1. Sunderland T,
    2. Hill JL,
    3. Mellow AM,
    4. et al
    . Clock drawing in Alzheimer's disease. A novel measure of dementia severity. J Am Geriatr Soc 1989;37:725–9.
    OpenUrlCrossRefPubMedWeb of Science
  45. 45.↵
    1. Levy BT,
    2. Bay C,
    3. Xu Y,
    4. et al
    . Test characteristics of faecal immunochemical tests (FIT) compared with optical colonoscopy. J Med Screen 2014;21:133–43.
    OpenUrlCrossRefPubMed
  46. 46.↵
    1. Johnson DA,
    2. Barkun AN,
    3. Cohen LB
    , US Multi-Society Task Force on Colorectal Canceret al. Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the US multi-society task force on colorectal cancer. Gastroenterology 2014;147:903–24.
    OpenUrlCrossRefPubMed
  47. 47.↵
    1. Davidson KW,
    2. Barry MJ,
    3. Mangione CM
    , US Preventive Services Task Forceet al. Screening for colorectal cancer: US Preventive Services Task Force Recommendation Statement. JAMA 2021;325:1965–77.
    OpenUrlCrossRefPubMed
  48. 48.↵
    1. Rex DK,
    2. Boland CR,
    3. Dominitz JA,
    4. et al
    . Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. Gastroenterology 2017;153:307–23.
    OpenUrlCrossRefPubMed
  49. 49.↵
    1. Kotwal AA,
    2. Walter LC
    . Cancer screening in older adults: individualized decision-making and communication strategies. Med Clin North Am 2020;104:989–1006.
    OpenUrlPubMed
  50. 50.↵
    1. Cheng RW,
    2. Chiu YC,
    3. Wu KL,
    4. et al
    . Predictive factors for inadequate colon preparation before colonoscopy. Tech Coloproctol 2015;19:111–5.
    OpenUrlPubMed
  51. 51.
    1. Cheng CL,
    2. Liu NJ,
    3. Tang JH,
    4. et al
    . Predictors of suboptimal bowel preparation using 3-l of polyethylene glycol for an outpatient colonoscopy: a prospective observational study. Dig Dis Sci 2017;62:345–51.
    OpenUrlPubMed
  52. 52.↵
    1. Fang J,
    2. Fu HY,
    3. Ma D,
    4. et al
    . Constipation, fiber intake and non-compliance contribute to inadequate colonoscopy bowel preparation: a prospective cohort study. J Dig Dis 2016;17:458–63.
    OpenUrlPubMed
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