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Research ArticlePriority Updates from the Research Literature (PURLs)

Piroxicam Plus Plan B for Emergency Contraception

J. Scott Earwood, Shirley L. Sharp, Ryan Cosby, Curtis M. Smith and Carina Brown
The Journal of the American Board of Family Medicine March 2025, 38 (2) 395-398; DOI: https://doi.org/10.3122/jabfm.2024.240432R0
J. Scott Earwood
From the Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (JSE); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (SLS); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (RC); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (CMS).
MD, FAAFP
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Shirley L. Sharp
From the Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (JSE); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (SLS); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (RC); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (CMS).
DO, MS, FACOFP
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Ryan Cosby
From the Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (JSE); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (SLS); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (RC); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (CMS).
DO, MS
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Curtis M. Smith
From the Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (JSE); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (SLS); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (RC); Department of Family and Community Medicine Medical College of Georgia at August University, Augusta, GA (CMS).
DO, MSADE
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Carina Brown
Cone Health Program, Greensboro, NC (E-mail: ).
MD
Roles: Editor:
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  • For correspondence: carina.brown{at}conehealth.com
  • Article
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References

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    1. Li RHW,
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    3. Gemzell-Danielsson K,
    4. Fong CHY,
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    6. Ng EHY
    . Oral emergency contraception with Levonorgestrel plus Piroxicam: a randomised double-blind placebo-controlled trial [published correction appears in Lancet. 2023 Sep 9;402(10405):850]. Lancet 2023;402:851–8.
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    Committee Opinion No 707: access to emergency contraception. Obstet Gynecol 2017;130:e48–e52.
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    . Does unwanted pregnancy lead to adverse health and healthcare utilization for mother and child? Evidence from low- and middle-income countries. Int J Public Health 2020;65:457–68.
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    1. Gemzell-Danielsson K
    . Mechanism of action of emergency contraception. Contraception 2010;82:404–9.
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    2. Godfrey EM,
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    , Nigerian Network for Reproductive Health Research and Training. A randomized, double-blind, noninferiority study to compare two regimens of Levonorgestrel for emergency contraception in Nigeria. Contraception 2010;82:373–8.
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    1. Glasier AF,
    2. Cameron ST,
    3. Fine PM,
    4. et al
    . Ulipristal acetate versus Levonorgestrel for emergency contraception: a randomised non-inferiority trial and meta-analysis [published correction appears in Lancet. 2014 Oct 25;384(9953):1504]. Lancet 2010;375:555–62.
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  8. 8.↵
    Randomised controlled trial of Levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Task Force on Postovulatory Methods of Fertility Regulation. Lancet 1998;352:428–33.
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  9. 9.↵
    1. Creinin MD,
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    . Progesterone receptor modulator for emergency contraception: a randomized controlled trial. Obstet Gynecol 2006;108:1089–97.
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  10. 10.↵
    1. Weiss EA,
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    . Preferential cyclooxygenase 2 inhibitors as a nonhormonal method of emergency contraception: a look at the evidence. J Pharm Pract 2016;29:160–4.
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  11. 11.↵
    1. Trussell J,
    2. Ellertson C,
    3. von Hertzen CH,
    4. et al
    . Estimating the effectiveness of emergency contraceptive pills. Contraception 2003;67:259–65. Issue Pages, ISSN 0010-7824.
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  12. 12.↵
    1. Festin MPR,
    2. Peregoudov A,
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    . Effect of BMI and body weight on pregnancy rates with LNG as emergency contraception: analysis of four WHO HRP studies. Contraception 2017;95:50–4.
    OpenUrlPubMed
  13. 13.↵
    1. Smith P,
    2. Castelli G
    . The priority updates from the research literature (PURLs) methodology. J Am Board Fam Med 2024;37:799–802. Published 2024 Oct 25.
    OpenUrlFREE Full Text
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The Journal of the American Board of Family     Medicine: 38 (2)
The Journal of the American Board of Family Medicine
Vol. 38, Issue 2
March-April 2025
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Piroxicam Plus Plan B for Emergency Contraception
J. Scott Earwood, Shirley L. Sharp, Ryan Cosby, Curtis M. Smith
The Journal of the American Board of Family Medicine Mar 2025, 38 (2) 395-398; DOI: 10.3122/jabfm.2024.240432R0

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Piroxicam Plus Plan B for Emergency Contraception
J. Scott Earwood, Shirley L. Sharp, Ryan Cosby, Curtis M. Smith
The Journal of the American Board of Family Medicine Mar 2025, 38 (2) 395-398; DOI: 10.3122/jabfm.2024.240432R0
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Keywords

  • Combination Drug Therapy
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