Response: Re: Presenting Signs of Multiple Myeloma and the Effect of Diagnostic Delay on the Prognosis ====================================================================================================== * Neta Goldschmidt *To the Editor:* We thank Dr. Gurmukh Singh for his response. We are not advocating screening for multiple myeloma using a serum-free light-chain assay, and we agree with Dr. Gurmukh Singh that no evidence exists for the efficacy of serum-free light-chain testing in asymptomatic individuals. However, we suggest that this might be a worthwhile diagnostic test for patients with unexplained back pain and other “red flag” signs or symptoms, in whom multiple myeloma is suspected. ## Notes * To see this article online, please go to: [http://jabfm.org/content/30/2/265.full](http://jabfm.org/content/30/2/000.full).