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Research ArticleOriginal Research

5-Day versus 10-Day Course of Fluoroquinolones in Outpatient Males with a Urinary Tract Infection (UTI)

Geoffrey A. Mospan and Kurt A. Wargo
The Journal of the American Board of Family Medicine November 2016, 29 (6) 654-662; DOI: https://doi.org/10.3122/jabfm.2016.06.160065
Geoffrey A. Mospan
the Wingate University School of Pharmacy, Hendersonville, NC.
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Kurt A. Wargo
the Wingate University School of Pharmacy, Hendersonville, NC.
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References

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    1. Khawcharoenporn T,
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    . High rates of quinolone resistance among urinary tract infections in the ED. Am J Emerg Med 2012;30:68–74.
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    1. Gottesman BS,
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    . Impact of quinolone restriction on resistance patterns of Escherichia coli isolated from urine by culture in a community setting. Clin Infect Dis 2009;49:869–75.
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    1. Zhanel GG,
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    . Antibiotic resistance in outpatient urinary isolates: final results from the North American Urinary Tract Infection Collaborative Alliance (NAUTICA). Int J Antimicrob Agents 2005;26:380–8.
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    . A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis. Urology 2008;71:17–22.
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    1. Dalhoff A
    . Global fluoroquinolone resistance epidemiology and implications for clinical use. Interdiscip Perspect Infect Dis 2012;2012:976273.
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    U.S. Food and Drug Administration. FDA drug safety communication. FDA advises restricting fluoroquinolone antibiotic use for certain uncomplicated infections; warns about disabling side effects that can occur together. May 12, 2016. Available from: http://www.fda.gov/downloads/Drugs/DrugSafety/UCM500591.pdf. Accessed May 16, 2016.
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    1. Liu HH
    . Safety profile of the fluoroquinolones: focus on levofloxacin. Drug Saf 2010;33:353–69.
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The Journal of the American Board of Family     Medicine: 29 (6)
The Journal of the American Board of Family Medicine
Vol. 29, Issue 6
November-December 2016
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5-Day versus 10-Day Course of Fluoroquinolones in Outpatient Males with a Urinary Tract Infection (UTI)
Geoffrey A. Mospan, Kurt A. Wargo
The Journal of the American Board of Family Medicine Nov 2016, 29 (6) 654-662; DOI: 10.3122/jabfm.2016.06.160065

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5-Day versus 10-Day Course of Fluoroquinolones in Outpatient Males with a Urinary Tract Infection (UTI)
Geoffrey A. Mospan, Kurt A. Wargo
The Journal of the American Board of Family Medicine Nov 2016, 29 (6) 654-662; DOI: 10.3122/jabfm.2016.06.160065
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Keywords

  • Antibacterial Agents
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  • Ciprofloxacin
  • Double-Blind Method
  • Levofloxacin
  • Outpatients
  • Urinary Tract Infections

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