Skip to main content

Main menu

  • Home
  • Articles
    • Current Issue
    • COVID-19
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Editors' Blog
    • Email Alerts
  • Info For
    • Authors
    • Reviewers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • About
    • The JABFM
    • Editorial Board
    • Indexing
  • Classifieds
  • More
    • Email Alerts
    • Feedback
    • ABFM News
    • Folders
    • Help
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • Home
  • Articles
    • Current Issue
    • COVID-19
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Editors' Blog
    • Email Alerts
  • Info For
    • Authors
    • Reviewers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • About
    • The JABFM
    • Editorial Board
    • Indexing
  • Classifieds
  • More
    • Email Alerts
    • Feedback
    • ABFM News
    • Folders
    • Help
  • JABFM On Twitter
  • JABFM On YouTube
  • JABFM On Facebook
Review ArticleClinical Review

Treatment of Acne in Pregnancy

Anna L. Chien, Ji Qi, Barbara Rainer, Dana L. Sachs and Yolanda R. Helfrich
The Journal of the American Board of Family Medicine March 2016, 29 (2) 254-262; DOI: https://doi.org/10.3122/jabfm.2016.02.150165
Anna L. Chien
the Department of Dermatology, Johns Hopkins University, Baltimore, MD (ALC, JQ, BR); and the Department of Dermatology, University of Michigan, Ann Arbor (DLS, YRH).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ji Qi
the Department of Dermatology, Johns Hopkins University, Baltimore, MD (ALC, JQ, BR); and the Department of Dermatology, University of Michigan, Ann Arbor (DLS, YRH).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Barbara Rainer
the Department of Dermatology, Johns Hopkins University, Baltimore, MD (ALC, JQ, BR); and the Department of Dermatology, University of Michigan, Ann Arbor (DLS, YRH).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dana L. Sachs
the Department of Dermatology, Johns Hopkins University, Baltimore, MD (ALC, JQ, BR); and the Department of Dermatology, University of Michigan, Ann Arbor (DLS, YRH).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yolanda R. Helfrich
the Department of Dermatology, Johns Hopkins University, Baltimore, MD (ALC, JQ, BR); and the Department of Dermatology, University of Michigan, Ann Arbor (DLS, YRH).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. 1.↵
    1. Akhavan A,
    2. Bershad S
    . Topical acne drugs: review of clinical properties, systemic exposure, and safety. Am J Clin Dermatol 2003;4:473–92.
    OpenUrlCrossRefPubMedWeb of Science
  2. 2.↵
    1. Jones SV,
    2. Ambros-Rudolph C,
    3. Nelson-Piercy C
    . Skin disease in pregnancy. BMJ 2014;348:g3489.
    OpenUrlFREE Full Text
  3. 3.↵
    1. Pugashetti R,
    2. Shinkai K
    . Treatment of acne vulgaris in pregnant patients. Dermatol Ther 2013;26:302–11.
    OpenUrlPubMed
  4. 4.↵
    1. Dréno B,
    2. Blouin E,
    3. Moyse D,
    4. Bodokh I,
    5. Knol A,
    6. Khammari A
    . Acne in pregnant women: a French survey. Acta Derm Venereol 2014;94:82–3.
    OpenUrlPubMed
  5. 5.↵
    1. Wolverton SE
    , ed. Comprehensive dermatologic drug therapy. 3rd ed. Philadelphia: Saunders; 2012.
  6. 6.↵
    1. Murase JE,
    2. Heller MM,
    3. Butler DC
    . Safety of dermatologic medications in pregnancy and lactation: part I. Pregnancy. J Am Acad Dermatol 2014;70:401.e1–14; quiz 415.
    OpenUrl
  7. 7.↵
    1. Williams HC,
    2. Dellavalle RP,
    3. Garner S
    . Acne vulgaris. Lancet 2012;379:361–72.
    OpenUrlCrossRefPubMedWeb of Science
  8. 8.↵
    1. Parry MF,
    2. Rha CK
    . Pseudomembranous colitis caused by topical clindamycin phosphate. Arch Dermatol 1986;122:583–4.
    OpenUrlCrossRefPubMedWeb of Science
  9. 9.↵
    1. Siegle RJ,
    2. Fekety R,
    3. Sarbone PD,
    4. Finch RN,
    5. Deery HG,
    6. Voorhees JJ
    . Effects of topical clindamycin on intestinal microflora in patients with acne. J Am Acad Dermatol 1986;15(2 Pt 1):180–5.
    OpenUrlPubMedWeb of Science
  10. 10.↵
    1. Patel M,
    2. Bowe WP,
    3. Heughebaert C,
    4. Shalita AR
    . The development of antimicrobial resistance due to the antibiotic treatment of acne vulgaris: a review. J Drugs Dermatol 2010;9:655–64.
    OpenUrlPubMedWeb of Science
  11. 11.↵
    1. Kinney MA,
    2. Yentzer BA,
    3. Fleischer AB,
    4. Feldman SR
    . Trends in the treatment of acne vulgaris: are measures being taken to avoid antimicrobial resistance? J Drugs Dermatol 2010;9:519–24.
    OpenUrlPubMed
  12. 12.↵
    1. Berard A,
    2. Azoulay L,
    3. Koren G,
    4. Blais L,
    5. Perreault S,
    6. Oraichi D
    . Isotretinoin, pregnancies, abortions and birth defects: a population-based perspective. Br J Clin Pharmacol 2007;63:196–205.
    OpenUrlCrossRefPubMedWeb of Science
  13. 13.↵
    1. Panchaud A,
    2. Csajka C,
    3. Merlob P
    . Pregnancy outcome following exposure to topical retinoids: prospective study. J Clin Pharmacol 2012;52:1844–51.
    OpenUrlCrossRefPubMed
  14. 14.↵
    1. Kaplan YC,
    2. Ozsarfati J,
    3. Etwel F,
    4. Nickel C,
    5. Nulman I,
    6. Koren G
    . Pregnancy outcomes following first trimester exposure to topical retinoids : a systematic review and meta-analysis. Br J Dermatol 2015;173:1132–41.
    OpenUrlPubMed
  15. 15.↵
    1. Gamble R,
    2. Dunn J,
    3. Dawson A,
    4. et al
    . Topical antimicrobial treatment of acne vulgaris: an evidence-based review. Am J Clin Dermatol 2012;13:141–52.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Nosten F,
    2. McGready R,
    3. d'Alessandro U,
    4. et al
    . Antimalarial drugs in pregnancy: a review. Curr Drug Saf 2006;1:1–15.
    OpenUrlCrossRefPubMed
  17. 17.↵
    1. James KA,
    2. Burkhart CN,
    3. Morrell DS
    . Emerging drugs for acne. Expert Opin Emerg Drugs 2009;14:649–59.
    OpenUrlPubMed
  18. 18.↵
    1. Kong YL,
    2. Tey HL
    . Treatment of acne vulgaris during pregnancy and lactation. Drugs 2013;73:779–87.
    OpenUrlPubMed
  19. 19.↵
    1. Thiboutot D,
    2. Gollnick H,
    3. Bettoli V,
    4. et al
    . New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne Group. J Am Acad Dermatol 2009;60(5 Suppl):S1–50.
    OpenUrlCrossRefPubMedWeb of Science
  20. 20.↵
    1. Romoren M,
    2. Lindbaek M,
    3. Nordeng H
    . Pregnancy outcome after gestational exposure to erythromycin-a population-based register study from Norway. Br J Clin Pharmacol 2012;74:1053–62.
    OpenUrlCrossRefPubMed
  21. 21.↵
    1. Al Hammadi A,
    2. Al-Haddab M,
    3. Sasseville D
    . Dermatologic treatment during pregnancy: practical overview. J Cutan Med Surg 2006;10:183–92.
    OpenUrlAbstract/FREE Full Text
  22. 22.↵
    1. Hale EK,
    2. Pomeranz MK
    . Dermatologic agents during pregnancy and lactation: an update and clinical review. Int J Dermatol 2002;41:197–203.
    OpenUrlCrossRefPubMedWeb of Science
  23. 23.↵
    1. Lin KJ,
    2. Mitchell AA,
    3. Yau W-P,
    4. Louik C,
    5. Hernández-Díaz S
    . Maternal exposure to amoxicillin and the risk of oral clefts. Epidemiology 2012;23:699–705.
    OpenUrlPubMed
  24. 24.↵
    1. Turowski CB,
    2. James WD
    . The efficacy and safety of amoxicillin, trimethoprim-sulfamethoxazole, and spironolactone for treatment-resistant acne vulgaris. Adv Dermatol 2007;23:155–63.
    OpenUrlPubMed
  25. 25.↵
    1. Fenner JA,
    2. Wiss K,
    3. Levin NA
    . Oral cephalexin for acne vulgaris: clinical experience with 93 patients. Pediatr Dermatol 2008;25:179–83.
    OpenUrlPubMed
  26. 26.↵
    1. Andersen JT,
    2. Petersen M,
    3. Jimenez-Solem E,
    4. et al
    . Trimethoprim use in early pregnancy and the risk of miscarriage: a register-based nationwide cohort study. Epidemiol Infect 2013;141:1749–55.
    OpenUrl
  27. 27.↵
    1. Park-Wyllie L,
    2. Mazzotta P,
    3. Pastuszak A,
    4. et al
    . Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies. Teratology 2000;62:385–92.
    OpenUrlCrossRefPubMedWeb of Science
  28. 28.↵
    1. Rennick GJ
    . Use of systemic glucocorticosteroids in pregnancy: be alert but not alarmed. Australas J Dermatol 2006;47:34–6.
    OpenUrlCrossRefPubMed
  29. 29.↵
    1. Gur C,
    2. Diav-Citrin O,
    3. Shechtman S,
    4. Arnon J,
    5. Ornoy A
    . Pregnancy outcome after first trimester exposure to corticosteroids: a prospective controlled study. Reprod Toxicol 2004;18:93–101.
    OpenUrlCrossRefPubMedWeb of Science
  30. 30.↵
    1. Dréno B,
    2. Blouin E
    . [Acne, pregnant women and zinc salts: a literature review]. Ann Dermatol Venereol 2008;135:27–33.
    OpenUrlPubMed
  31. 31.↵
    1. Brocard A,
    2. Dréno B
    . Innate immunity: a crucial target for zinc in the treatment of inflammatory dermatosis. J Eur Acad Dermatol Venereol 2011;25:1146–52.
    OpenUrlPubMed
  32. 32.↵
    1. Brandt S
    . The clinical effects of zinc as a topical or oral agent on the clinical response and pathophysiologic mechanisms of acne: a systematic review of the literature. J Drugs Dermatol 2013;12:542–5.
    OpenUrlPubMed
  33. 33.↵
    1. Taub AF
    . Procedural treatments for acne vulgaris. Dermatol Surg 2007;33:1005–26.
    OpenUrlPubMed
  34. 34.↵
    1. Hongcharu W,
    2. Taylor CR,
    3. Chang Y,
    4. Aghassi D,
    5. Suthamjariya K,
    6. Anderson RR
    . Topical ALA-photodynamic therapy for the treatment of acne vulgaris. J Invest Dermatol 2000;115:183–92.
    OpenUrlCrossRefPubMedWeb of Science
  35. 35.↵
    1. de Leeuw J,
    2. van der Beek N,
    3. Bjerring P,
    4. Neumann HAM
    . Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid 0.5% liposomal spray and intense pulsed light in combination with topical keratolytic agents. J Eur Acad Dermatol Venereol 2010;24:460–9.
    OpenUrlPubMed
  36. 36.
    1. Dréno B,
    2. Layton A,
    3. Zouboulis CC,
    4. et al
    . Adult female acne: a new paradigm. J Eur Acad Dermatol Venereol 2013;27:1063–70.
    OpenUrlPubMed
  37. 37.
    1. Purdy S,
    2. de Berker D
    . Acne vulgaris. BMJ Clin Evid 2011;2011. pii. 1714.
PreviousNext
Back to top

In this issue

The Journal of the American Board of Family     Medicine: 29 (2)
The Journal of the American Board of Family Medicine
Vol. 29, Issue 2
March-April 2016
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Treatment of Acne in Pregnancy
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
1 + 3 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Treatment of Acne in Pregnancy
Anna L. Chien, Ji Qi, Barbara Rainer, Dana L. Sachs, Yolanda R. Helfrich
The Journal of the American Board of Family Medicine Mar 2016, 29 (2) 254-262; DOI: 10.3122/jabfm.2016.02.150165

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Treatment of Acne in Pregnancy
Anna L. Chien, Ji Qi, Barbara Rainer, Dana L. Sachs, Yolanda R. Helfrich
The Journal of the American Board of Family Medicine Mar 2016, 29 (2) 254-262; DOI: 10.3122/jabfm.2016.02.150165
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Literature Search and Data Sources
    • Topical Treatments
    • Oral Treatments
    • Procedure-Based Treatment
    • Summary of Recommendations
    • Notes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • The Most Frequently Read Articles of 2019
  • Content Usage and the Most Frequently Read Articles of 2018
  • Content Usage and the Most Frequently Read Articles of 2016
  • Outcomes of Health System Structures, Highly Pertinent Clinical Information, Idea Stimulators, Clinical Reviews, and Prediction Tools: JABFM Exemplified
  • Google Scholar

More in this TOC Section

  • Practical Management of Common Skin Injuries, Lacerations, Wounds, Trigger Fingers, and Burns
  • Diagnosis and Management of Atopic Dermatitis for Primary Care Providers
  • Breast Cancer Screening in Older Women: The Importance of Shared Decision Making
Show more Clinical Reviews

Similar Articles

Keywords

  • Acne
  • Dermatology
  • Maternal Health
  • Pregnancy

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us

© 2021 American Board of Family Medicine

Powered by HighWire