Skip to main content

Main menu

  • Home
  • Articles
    • Current Issue
    • COVID-19
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Editors' Blog
    • Email Alerts
  • Info For
    • Authors
    • Reviewers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • About
    • The JABFM
    • Editorial Board
    • Indexing
  • Classifieds
  • More
    • Email Alerts
    • Feedback
    • ABFM News
    • Folders
    • Help
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • Home
  • Articles
    • Current Issue
    • COVID-19
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Editors' Blog
    • Email Alerts
  • Info For
    • Authors
    • Reviewers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • About
    • The JABFM
    • Editorial Board
    • Indexing
  • Classifieds
  • More
    • Email Alerts
    • Feedback
    • ABFM News
    • Folders
    • Help
  • JABFM On Twitter
  • JABFM On YouTube
  • JABFM On Facebook
Research ArticleAbout Practice-Based Research Networks

Guidance for Researchers Developing and Conducting Clinical Trials in Practice-based Research Networks (PBRNs)

Rowena J. Dolor, Kristine M. Schmit, Deborah G. Graham, Chester H. Fox and Laura Mae Baldwin
The Journal of the American Board of Family Medicine November 2014, 27 (6) 750-758; DOI: https://doi.org/10.3122/jabfm.2014.06.140166
Rowena J. Dolor
the Duke Clinical Research Institute, Duke University, Durham, NC (RJD); Department of Community and Family Medicine, Duke University Medical Center, Durham, NC (KMS); American Academy of Family Physicians National Research Network, Leawood, KS (DGG); DARTNet Institute, Wilmette, IL (DGG); Department of Family Medicine, University of Buffalo, Buffalo, NY (CHF); and the Department of Family Medicine, University of Washington, Seattle, WA (LMB).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kristine M. Schmit
the Duke Clinical Research Institute, Duke University, Durham, NC (RJD); Department of Community and Family Medicine, Duke University Medical Center, Durham, NC (KMS); American Academy of Family Physicians National Research Network, Leawood, KS (DGG); DARTNet Institute, Wilmette, IL (DGG); Department of Family Medicine, University of Buffalo, Buffalo, NY (CHF); and the Department of Family Medicine, University of Washington, Seattle, WA (LMB).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Deborah G. Graham
the Duke Clinical Research Institute, Duke University, Durham, NC (RJD); Department of Community and Family Medicine, Duke University Medical Center, Durham, NC (KMS); American Academy of Family Physicians National Research Network, Leawood, KS (DGG); DARTNet Institute, Wilmette, IL (DGG); Department of Family Medicine, University of Buffalo, Buffalo, NY (CHF); and the Department of Family Medicine, University of Washington, Seattle, WA (LMB).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chester H. Fox
the Duke Clinical Research Institute, Duke University, Durham, NC (RJD); Department of Community and Family Medicine, Duke University Medical Center, Durham, NC (KMS); American Academy of Family Physicians National Research Network, Leawood, KS (DGG); DARTNet Institute, Wilmette, IL (DGG); Department of Family Medicine, University of Buffalo, Buffalo, NY (CHF); and the Department of Family Medicine, University of Washington, Seattle, WA (LMB).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Laura Mae Baldwin
the Duke Clinical Research Institute, Duke University, Durham, NC (RJD); Department of Community and Family Medicine, Duke University Medical Center, Durham, NC (KMS); American Academy of Family Physicians National Research Network, Leawood, KS (DGG); DARTNet Institute, Wilmette, IL (DGG); Department of Family Medicine, University of Buffalo, Buffalo, NY (CHF); and the Department of Family Medicine, University of Washington, Seattle, WA (LMB).
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

Abstract

Background: There is increased interest nationally in multicenter clinical trials to answer questions about clinical effectiveness, comparative effectiveness, and safety in real-world community settings. Primary care practice-based research networks (PBRNs), comprising community- and/or academically affiliated practices committed to improving medical care for a range of health problems, offer ideal settings for these trials, especially pragmatic clinical trials. However, many researchers are not familiar with working with PBRNs.

Methods: Experts in practice-based research identified solutions to challenges that researchers and PBRN personnel experience when collaborating on clinical trials in PBRNs. These were organized as frequently asked questions in a draft document presented at a 2013 Agency for Health care Research and Quality PBRN conference workshop, revised based on participant feedback, then shared with additional experts from the DARTNet Institute, Clinical Translational Science Award PBRN, and North American Primary Care Research Group PBRN workgroups for further input and modification.

Results: The “Toolkit for Developing and Conducting Multi-site Clinical Trials in Practice-Based Research Networks” offers guidance in the areas of recruiting and engaging practices, budgeting, project management, and communication, as well as templates and examples of tools important in developing and conducting clinical trials.

Conclusion: Ensuring the successful development and conduct of clinical trials in PBRNs requires a highly collaborative approach between academic research and PBRN teams.

  • Clinical Trials as Topic
  • Practice-based Research
View Full Text
PreviousNext
Back to top

In this issue

The Journal of the American Board of Family     Medicine: 27 (6)
The Journal of the American Board of Family Medicine
Vol. 27, Issue 6
November-December 2014
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Guidance for Researchers Developing and Conducting Clinical Trials in Practice-based Research Networks (PBRNs)
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
1 + 5 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Guidance for Researchers Developing and Conducting Clinical Trials in Practice-based Research Networks (PBRNs)
Rowena J. Dolor, Kristine M. Schmit, Deborah G. Graham, Chester H. Fox, Laura Mae Baldwin
The Journal of the American Board of Family Medicine Nov 2014, 27 (6) 750-758; DOI: 10.3122/jabfm.2014.06.140166

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Guidance for Researchers Developing and Conducting Clinical Trials in Practice-based Research Networks (PBRNs)
Rowena J. Dolor, Kristine M. Schmit, Deborah G. Graham, Chester H. Fox, Laura Mae Baldwin
The Journal of the American Board of Family Medicine Nov 2014, 27 (6) 750-758; DOI: 10.3122/jabfm.2014.06.140166
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • Appendix 1
    • Notes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Clinician and Staff Perspectives on Participating in Practice-based Research (PBR): A Report from the Wisconsin Research and Education Network (WREN)
  • Practice-based Research Networks at the Crossroads of Research Translation
  • Google Scholar

More in this TOC Section

  • Practice-based Research Networks (PBRNs) Bridging the Gaps between Communities, Funders, and Policymakers
  • Lessons Learned from Developing a Patient Engagement Panel: An OCHIN Report
  • Lessons from Initiating the First Veterans Health Administration (VA) Women's Health Practice-based Research Network (WH-PBRN) Study
Show more About Practice-Based Research Networks

Similar Articles

Keywords

  • Clinical Trials as Topic
  • Practice-Based Research

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us

© 2021 American Board of Family Medicine

Powered by HighWire