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Research ArticleOriginal Research

Clinical Importance of Purulence in Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections

Susan E. Crawford, Michael Z. David, Daniel Glikman, Kimberly J. King, Susan Boyle-Vavra and Robert S. Daum
The Journal of the American Board of Family Medicine November 2009, 22 (6) 647-654; DOI: https://doi.org/10.3122/jabfm.2009.06.090025
Susan E. Crawford
MD
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Michael Z. David
MD, PhD
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Daniel Glikman
MD
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Kimberly J. King
MS
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Susan Boyle-Vavra
PhD
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Robert S. Daum
MD
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  • Article
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References

  1. ↵
    Barber M. Methicillin-resistant staphylococci. J Clin Pathol 1961; 14: 385–93.
    OpenUrlAbstract/FREE Full Text
  2. ↵
    Barrett FF, McGehee RF, Finland M. Methicillin-resistant Staphylococcus aureus at Boston City Hospital. N Eng J Med 1968; 279: 441–8.
    OpenUrlPubMedWeb of Science
  3. ↵
    Doebbeling BN. The epidemiology of methicillin-resistant Staphylococcus aureus colonisation and infection. J Chemother 1995; 7(Suppl 3): 99–103.
    OpenUrl
  4. ↵
    Herold BC, Immergluck LC, Maranan MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA 1998; 279: 593–8.
    OpenUrlCrossRefPubMedWeb of Science
  5. ↵
    Centers for Disease Control and Prevention. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997–1999. MMWR Morb Mortal Wkly Rep 1999; 48: 707–10.
    OpenUrlPubMed
  6. ↵
    Naimi TS, LeDell KH, Como-Sabetti K, et al. Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA 2003; 290: 2976–84.
    OpenUrlCrossRefPubMedWeb of Science
  7. ↵
    Ito T, Katayama Y, Asada K, et al. Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2001; 45: 1323–36.
    OpenUrlAbstract/FREE Full Text
  8. ↵
    Diep BA, Chambers HF, Graber CJ, et al. Emergence of multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus clone USA300 in men who have sex with men. Ann Intern Med 2008; 148: 249–57.
    OpenUrlCrossRefPubMedWeb of Science
  9. ↵
    Han LL, McDougal LK, Gorwitz RJ, et al. High frequencies of clindamycin and tetracycline resistance in methicillin-resistant Staphylococcus aureus pulsed-field type USA300 isolates collected at a Boston ambulatory health center. J Clin Microbiol 2007; 45: 1350–2.
    OpenUrlAbstract/FREE Full Text
  10. ↵
    Ma XX, Ito T, Tiensasitorn C, et al. Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains. Antimicrob Agents Chemother 2002; 46: 1147–52.
    OpenUrlAbstract/FREE Full Text
  11. ↵
    Daum RS, Ito T, Hiramatsu K, et al. A novel methicillin-resistance cassette in community-acquired methicillin-resistant Staphylococcus aureus isolates of diverse genetic backgrounds. J Infect Dis 2002; 186: 1344–7.
    OpenUrlAbstract/FREE Full Text
  12. Vandenesch F, Naimi T, Enright MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis 2003; 9: 978–84.
    OpenUrlCrossRefPubMedWeb of Science
  13. ↵
    Fridkin SK, Hageman JC, Morrison M, et al. Active Bacterial Core Surveillance Program of the Emerging Infections Program Network. Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med 2005; 352: 1436–44.
    OpenUrlCrossRefPubMedWeb of Science
  14. ↵
    Adem PV, Montgomery CP, Husain AN, et al. Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children. N Engl J Med 2005; 353: 1245–51.
    OpenUrlCrossRefPubMedWeb of Science
  15. Francis JS, Doherty MC, Lopatin U, et al. Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. Clin Infect Dis 2005; 40: 100–7.
    OpenUrlAbstract/FREE Full Text
  16. Miller LG, Perdreau-Remington F, Rieg G, et al. Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med 2005; 352: 1445–53.
    OpenUrlCrossRefPubMedWeb of Science
  17. ↵
    Diekema DJ, Pfaller MA, Schmitz FJ, et al. Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997–1999. Clin Infect Dis 2001; 32(Suppl): S114–32.
    OpenUrlAbstract/FREE Full Text
  18. ↵
    Charlebois ED, Perdreau-Remington F, Kreiswirth B, et al. Origins of community strains of methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2004; 39: 47–54.
    OpenUrlAbstract/FREE Full Text
  19. Klevens RM, Morrison MA, Nadle J, et al. Active Bacterial Core Surveillance MRSA Investigators. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 2007; 298: 1763–71.
    OpenUrlCrossRefPubMedWeb of Science
  20. ↵
    David MZ, Glikman D, Crawford SE, et al. What is community-associated methicillin-resistant Staphylococcus aureus? J Infect Dis 2008; 197: 1235–43.
    OpenUrlAbstract/FREE Full Text
  21. ↵
    Maree CL, Daum RS, Boyle-Vavra S, Matayoshi K, Miller LG. Community-associated methicillin-resistant Staphylococcus aureus isolates causing healthcare-associated infections. Emerg Infect Dis 2007; 13: 236–42.
    OpenUrlCrossRefPubMedWeb of Science
  22. Gonzalez BE, Rueda AM, Shelburne SA 3rd, Musher DM, Hamill RJ, Hulten KG. Community-associated strains of methicillin-resistant Staphylococcus aureus as the cause of healthcare-associated infection. Infect Control Hosp Epidemiol 2006; 27: 1051–6.
    OpenUrlCrossRefPubMedWeb of Science
  23. Healy CM, Hulten KG, Palazzi DL, Campbell JR, Baker CJ. Emergence of new strains of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit. Clin Infect Dis 2004; 39: 1460–6.
    OpenUrlAbstract/FREE Full Text
  24. Saiman L, O'Keefe M, Graham PL 3rd, et al. Hospital transmission of community-acquired methicillin-resistant Staphylococcus aureus among postpartum women. Clin Infect Dis 2003; 37: 1313–9.
    OpenUrlAbstract/FREE Full Text
  25. Klevens RM, Morrison MA, Fridkin SK, et al. Community-associated methicillin-resistant Staphylococcus aureus and healthcare risk factors. Emerg Infect Dis 2006; 12: 1991–3.
    OpenUrlCrossRefPubMedWeb of Science
  26. ↵
    National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial disk susceptibility testing. 14th Informational Supplement. Villanova, PA: National Committee for Clinical Laboratory Standards; 2004.
  27. ↵
    David MZ, Crawford SE, Boyle-Vavra S, Hostetler MA, Kim DC, Daum RS. Contrasting pediatric and adult methicillin-resistant Staphylococcus aureus isolates. Emerg Infect Dis 2006; 12: 631–7.
    OpenUrlCrossRefPubMedWeb of Science
  28. ↵
    Boyle-Vavra S, Ereshefsky B, Wang CC, Daum RS. Successful multiresistant community-associated methicillin-resistant Staphylococcus aureus lineage from Taipei, Taiwan, that carries either the novel Staphylcoccal chromosome cassette (SCCmec) type VT or SCCmec type IV. J Clin Micro 2005; 43: 4719–30.
    OpenUrlAbstract/FREE Full Text
  29. ↵
    Kaplan SL, Hulten KG, Gonzalez BE, et al. Three-year surveillance of community-acquired Staphylococcus aureus infections in children. Clin Infect Dis 2005; 40: 1785–91.
    OpenUrlAbstract/FREE Full Text
  30. ↵
    Moran GJ, Krishnadasan A, Gorwitz RJ, et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med 2006; 355: 666–74.
    OpenUrlCrossRefPubMedWeb of Science
  31. ↵
    Daum RS. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. N Engl J Med 2007; 357: 380–90.
    OpenUrlCrossRefPubMedWeb of Science
  32. ↵
    Frank AL, Marcinak JF, Mangat PD, et al. Clindamycin treatment of methicillin-resistant Staphylococcus aureus infections in children. Pediatr Infect Dis J 2002; 21: 530–4.
    OpenUrlCrossRefPubMedWeb of Science
  33. ↵
    Szumowski JD, Cohen DE, Kanaya F, Mayer KH. Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic. Antimicrob Agents Chemother 2007; 51: 423–8.
    OpenUrlAbstract/FREE Full Text
  34. ↵
    Voyich JM, Otto M, Mathema B, et al. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J Infect Dis 2006; 194: 1761–70.
    OpenUrlAbstract/FREE Full Text
  35. ↵
    Labandeira-Rey M, Couzon F, Boisset S, et al. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science 2007; 23: 1130–3.
    OpenUrl
  36. ↵
    Ward PD, Turner WH. Identification of staphylococcal Panton-Valentine leukocidin as a potent dermonecrotic toxin. Infect Immun 1980; 28: 393–7
    OpenUrlAbstract/FREE Full Text
  37. ↵
    Miller LG, Perdreau-Remington F, Bayer AS, et al. Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus infection from methicillin-susceptible S. aureus infection: a prospective investigation. Clin Infect Dis 2007; 44: 471–82.
    OpenUrlAbstract/FREE Full Text
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The Journal of the American Board of Family Medicine: 22 (6)
The Journal of the American Board of Family Medicine
Vol. 22, Issue 6
November-December 2009
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Clinical Importance of Purulence in Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections
Susan E. Crawford, Michael Z. David, Daniel Glikman, Kimberly J. King, Susan Boyle-Vavra, Robert S. Daum
The Journal of the American Board of Family Medicine Nov 2009, 22 (6) 647-654; DOI: 10.3122/jabfm.2009.06.090025

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Clinical Importance of Purulence in Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections
Susan E. Crawford, Michael Z. David, Daniel Glikman, Kimberly J. King, Susan Boyle-Vavra, Robert S. Daum
The Journal of the American Board of Family Medicine Nov 2009, 22 (6) 647-654; DOI: 10.3122/jabfm.2009.06.090025
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