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The Journal of the American Board of Family Medicine 22 (1): 79-83 (2009)
DOI: 10.3122/jabfm.2009.01.070247
© 2009 American Board of Family Medicine
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Brief Report

Lemierre Syndrome Following Oropharyngeal Infection: A Case Series

Miranda D. Lu, MD, Zubin Vasavada, MD and Christina Tanner, MD

From the Department of Family Medicine, University of Washington, Seattle

Correspondence: Corresponding author: Miranda D. Lu, MD, Department of Family Medicine, University of Washington, Box 354775, 4245 Roosevelt Way NE, Seattle, WA 98105 (E-mail: mir.d.lu{at}gmail.com)

Lemierre syndrome is a potentially fatal complication of oropharyngeal infections that is characterized by jugular vein thrombosis and septic emboli. Fusobacterium spp. are the causative organisms. Patients typically present with high fevers, neck pain, and pulmonary symptoms. Prompt clinical diagnosis and treatment with appropriate antibiotics are critical. Anticoagulation for this syndrome is controversial. We present 3 cases within a 12-month period of young, family practice patients seen with oropharyngeal infections who developed Lemierre syndrome. The incidence of Lemierre syndrome may be increasing and primary care physicians should be aware of this rare though serious condition.


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