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The Journal of the American Board of Family Medicine 21 (6): 562-568 (2008)
DOI: 10.3122/jabfm.2008.06.080080
© 2008 American Board of Family Medicine
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Clinical Review

Obesity: Effects on Cardiovascular Disease and its Diagnosis

Boban Mathew, MD, MRCP, DM, Lisa Francis, MD, MRCP, Attila Kayalar, MD and Jesse Cone, MD

Department of Cardiology (BM, AK, JC), State University of New York Upstate Medical University, Syracuse
Department of Internal Medicine (LF), State University of New York Upstate Medical University, Syracuse

Correspondence: Corresponding author: Boban Mathew, MD, MRCP, DM, Department of Cardiology, SUNY Upstate Medical University, 750 East Adam Street, Syracuse, NY 13210 (E-mail:bmathew6{at}yahoo.com)

The higher prevalence of cardiovascular disease in obese individuals is indirectly mediated, to a large extent, by the increased frequency of various well known risk factors like hypertension, diabetes, and dyslipidemia, either individually or as part of the metabolic syndrome. However, there are several ways in which obesity directly affects the cardiovascular system; these will be discussed in detail. We also focus on various challenges posed by obesity in the performance and interpretation of cardiac investigations and how they can be addressed.



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