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The Journal of the American Board of Family Medicine 21 (6): 512-521 (2008)
DOI: 10.3122/jabfm.2008.06.080025
© 2008 American Board of Family Medicine
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Original Research

Blood Pressure Control and Pharmacotherapy Patterns in the United States Before and After the Release of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) Guidelines

James H. Jackson, PharmD, MPH, John Sobolski, MD, PhD, Russ Krienke, MD, Ken S. Wong, PharmD, Feride Frech-Tamas, PharmD, MPH and Brian Nightengale, PhD

Xcenda, Palm Harbor, FL (JHJ, BN)
Section of Cardiology, Advocate Health Care, Chicago, IL (JS)
Austin Regional Clinic, TX (RK)
Department of Evidence-Based Medicine, Novartis Pharmaceuticals Corporation, East Hanover, NJ (KSW, FF-T)

Correspondence: Corresponding author: James H. Jackson, Senior Director, Xcenda, 4114 Woodlands Parkway, Suite 500, Palm Harbor, FL 34685 (E-mail: jay.jackson{at}xcenda.com)

Objectives: Despite recommendations from the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7), only 36.8% of patients were at target blood pressure (BP) in 2003 and 2004. The objective of this study was to assess improvements in BP control and treatment patterns before and after the publication of JNC 7.

Methods: This was a retrospective, time series analysis of 27 provider groups and managed care organizations from 1998 through 2006. Patients with hypertension were identified from more than 4000 physicians. Medical charts were collected and clinical data were evaluated using prevailing JNC criteria during the time period before and after JNC 7.

Results: A total of 19,258 patients were identified with hypertension: 15,258 included in the before-JNC 7 cohort and 4,000 in the after-JNC 7 cohort. BP control in the before-JNC 7 cohort was 40.8% compared with 49.3% in the after-JNC 7 cohort (P < .0001). After controlling for demographic and clinical covariates, patients in the before-JNC 7 cohort were 45% less likely to achieve BP control compared with the after-JNC 7 cohort (odds ratio, 0.551; P < .0001).

Conclusion: Although findings indicate BP control is improving, a significant need for further improvement remains.


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