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The Journal of the American Board of Family Medicine 19:418-421 (2006)
© 2006 American Board of Family Medicine

Brief Report

Carvedilol Suppresses Intractable Hiccups

Danielle Stueber, MD and Conrad M. Swartz, PhD, MD

Department of Psychiatry, Southern Illinois University School of Medicine, Springfield
Virginia Mason Medical Center, Seattle, WA

Correspondence: Corresponding author: Danielle Stueber, MD, Virginia Mason Medical Center, Graduate Medical Education H8, GME, 925 Seneca Street, Seattle, WA 98101 (E-mail: danielle.stueber{at}gmail.com)

Carvedilol (6.25 mg, 4 times daily) relieved 2 years of constant hiccupping, marked tardive dyskinesia, compulsive self-induced vomiting, and feelings of hopelessness and low mood in a 59-year-old African-American man. He previously failed trials of ranitidine, chlorpromazine, promethazine, tegaserod, ondansetron, metoclopramide, pantoprazole, pyloric injections of botulinum toxin A, and a vagal nerve stimulator. At a 5-month follow-up, improvement was maintained; there had been several instances of rapid relapse on carvedilol discontinuation.


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Copyright © 2006 by the American Board of Family Medicine.