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The Journal of the American Board of Family Medicine 19:191-194 (2006)
© 2006 American Board of Family Medicine


Brief Report

Copper Deficiency as Cause of Unexplained Hematologic and Neurologic Deficits in Patient with Prior Gastrointestinal Surgery

Joanne Wu, MD, MPH, Mari Ricker, MD and John Muench, MD, MPH

From the Oregon Health and Science University, Portland, OR

Correspondence: Corresponding author: Mari Ricker, MD, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239

Copper is a trace mineral essential to hematopoiesis and to the structure and function of the nervous system. Copper deficiency is a rare cause of anemia, leukopenia, and myeloneuropathy, but should be considered in the differential diagnosis in a patient with prior gastrointestinal surgery. We report the case of a 51-year-old woman admitted for nonspecific neurologic symptoms ultimately found to be due to copper malabsorption.





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J. Neurol. Neurosurg. PsychiatryHome page
C I Prodan, S S Bottomley, N R Holland, and S E Lind
Relapsing hypocupraemic myelopathy requiring high-dose oral copper replacement.
J. Neurol. Neurosurg. Psychiatry, September 1, 2006; 77(9): 1092 - 1093.
[Abstract] [Full Text] [PDF]




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