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Managing Gastroesophageal Reflux Disease in Primary Care: The Patient Perspective

From the David Geffen School of Medicine at UCLA, Beverly Hills, California (HL); Centre for Integrated Health Care Research, University of Durham, United Kingdom (PH); Outcomes Research, AstraZeneca R&D, Mölndal, Sweden (IW); and Department of Public Health and Primary Health Care, The University of Bergen, Norway (IW)

Correspondence: Corresponding author: Harley Liker, MD, MBA, David Geffen School of Medicine at UCLA, 9675 Brighton Way Suite 350, Beverly Hills, CA 90210 (e-mail: hliker{at}mednet.ucla.edu)

Gastroesophageal reflux disease (GERD) is a chronic disease that affects up to 20% of the population of Western countries and accounts for around 5% of a primary-care physician’s workload. A better understanding of how GERD affects many aspects of patients’ lives may aid the management of patients in primary care. We conducted a systematic review of the effect of GERD on health-related quality of life (HRQL) in the primary-care setting and in the community. Validated questionnaires have shown that GERD patients consulting in primary care experience substantial reductions in both physical and psychosocial aspects of HRQL, as well as work productivity. Impairments in HRQL are seen whether or not reflux esophagitis or Barrett’s esophagus is present on endoscopy, and are comparable with or worse than those seen in patients with other chronic diseases such as heart disease, diabetes, and cancer. Surveys in primary care and in the community highlight disrupted sleep, reduced concentration at work, and interference with physical activities such as exercise, housework, and gardening. Psychosocial aspects of patient well-being are also impaired, including enjoyment of social gatherings, intimacy, sex, and many individuals with GERD remain worried about the underlying cause of their symptoms. In conclusion, many aspects of HRQL are impaired in GERD patients. The primary-care physician is uniquely placed to assess and address the impact of GERD on patients’ lives.