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The Journal of the American Board of Family Practice 18:211-217 (2005)
© 2005 American Board of Family Practice

Evidence-Based Clinical Practice

Patients with a Family History of Cancer: Identification and Management

Margaret M. Eberl, MD, MPH, Annette Y. Sunga, MD, MPH, Carolyn D. Farrell, MS, CNP, CGC and Martin C. Mahoney, MD, PhD, FAAFP

Division of Cancer Prevention and Population Sciences (MME, AYS, MCM), Roswell Park Cancer Institute, Buffalo, New York
Department of Cancer Genetics, Clinical Genetics Service (CDF), Roswell Park Cancer Institute, Buffalo, New York
Department of Social and Preventive Medicine, School of Public Health and Health Professions (MME, AYS, MCM), State University of New York at Buffalo
Department of Family Medicine, School of Medicine and Biomedical Sciences (MME, AYS, MCM), State University of New York at Buffalo

Correspondence: Address correspondence to Margaret M. Eberl, MD, MPH, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Carlton 307, Elm and Carlton Streets, Buffalo, NY 14263 (e-mail: margaret.eberl{at}roswellpark.org)

A family history of certain malignancies, especially breast, ovarian, colorectal, and prostate cancers, can place persons at increased risk of developing these cancers. By constructing a pedigree that includes 3 generations, family physicians can identify patients at increased risk because of family cancer history. Persons at increased cancer risk because of family history warrant a surveillance strategy for early detection. Genetic professionals represent an important resource in assessing genetic risk and possible testing. Persons identified as being at increased risk of various cancers based on their family history should understand the surveillance plan that is recommended and the importance of maintaining a healthy lifestyle and remaining up to date on other cancer screening tests.


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Copyright © 2005 by the American Board of Family Medicine.