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Brief Report |
From the Department of Family Medicine, Stony Brook University, Stony Brook, NY
Correspondence: Address correspondence to Robert S. Bobrow, 20 Pinewood Dr., Commack, NY 11725 (e-mail: rbobrow{at}notes.cc.sunysb.edu)
Background: Elevations of coagulation factor VIII have recently been described in significant numbers of patients with venous thromboembolism (VTE) previously thought to have had an "idiopathic" event. Three patients from a family practice are presented with recurrent VTE and increased factor VIII levels.
Method: The case histories and results of laboratory tests were reviewed.
Results: The 3 patients had no other clear coagulopathy. In 2 of the 3, the increase was confirmed with a second reading.
Conclusions: Factor VIII assay should be considered in the work-up of idiopathic, recurrent VTE. Long-term anticoagulation may be appropriate in this setting.
This article has been cited by other articles:
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M. Hoffman Excess Factor VIII and Hypercoagulability J Am Board Fam Med, July 1, 2005; 18(4): 328 - 328. [Full Text] [PDF] |
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